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RMRC No. RMRC13033 Order
Strain/Stock Designation C57BL/6-Tg(Alb-HBx)A106Tfts/Narl
Status
EM| (Cryopreserved Embryos)
Availability Level4
Pricing (Embryos)  International:560USD
(Cryo Recovery)  International:760USD
Last Update Date 2016/12/19
Analysis Data
  • Description
  • Genes &
    alleles
  • Phenotype
  • Health &
    husbandry
  • References
  • Specific Term
    and Conditions
  • Construct map
Species laboratory mouse
Strain Type COI (coisogenic strain),MSR (mutant strain)
Mutant Type TG (Transgenic)
Other Names
Background Strain C57BL/6
Strain Description
1.  Liver-Specific expression of the HBV X protein, which was driven by Albumin promoter. 
2.  The HBx transgenic mice spontaneously develop hepatocellular carcinoma at 17 to 20 months of age, and the transgenic mice provide an animal model for evaluating chemopreventive and new therapeutic agents for HCC under physiologic conditions.
Depositor
Tsai, Ting-Fen / 蔡亭芬
Email
Allele Symbol Tg(Alb-HBx)A106Tfts
Allele Name Transgene insertion A106, Ting-Fen Tsai
Allele Description
Strain of Origin C57BL/6
Gene Symbol Alb
Gene Name Albumin promoter
Chromosome UN
Genotyping Method Download            
Genotyping NLAC            
Research Application
Cancer Metabolism
Pharmacology and Toxicology
Construction Technologies No
Animal Health Reports
Colony Maintenance
Breeding & Husbandry
Colony Maintenance
Mating System
hetero/hemi x wild type
References PubMed ID: 18339886

Specific Terms of Use
有特別規定
本生物材料僅限使用於學術研究。寄存者對於分讓申請人使用本材料 所獲得之研究成果,不主張任何專利、智慧財產權及其他財產權
DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of BIOLOGICAL RESOURCE for academic research purpose.
分讓申請人公開發表使用本材料所獲得之論文或其他研究成果時,應引用下述已發表之論文: Wu et al., Biochemical and Biophysical Research Communications 340: 916-958(2006); Wu et al., Cancer Research 68(6): 2033-204(2008)
Should the use of this material result in one or more scientific
publication(s) the recipient agrees to cite the paper(s): Wu et al., Biochemical and Biophysical Research Communications 340: 916-958(2006); Wu et al., Cancer Research 68(6): 2033-204(2008)
分讓申請人公開發表使用本材料所獲得之論文或其他研究成果時,應揭露並致謝本材料係由Dr. Ting-Fen Tsai, National Yang-Ming University所提供
Should the use of this material result in one or more scientific publication(s) the Recipient Investigator agrees to mention and acknowledge Dr. Ting-Fen Tsai, National Yang-Ming University
分讓申請人向國研院動物中心國家實驗鼠種原庫(NLAC-RMRC)申請本材料時,應附上寄存人簽名之授權分讓同意書作為附件;NLAC- RMRC 在取得寄存人書面同意後,始進行此材料之分讓。
The recipient should obtain a written consent from the depositor of the BIOLOGICAL RESOURCE, prior to NLAC-RMRC accepting the material distribution request.
Depositor Email:
Construct Map
 
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