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RMRC No. RMRC13164 Order
Strain/Stock Designation 129-Cacna1htm2IBMS/CCCTg(Myh7-YFP)IBMS/CCC
Status
EM| (Cryopreserved Embryos)
Availability Level4
Pricing (Embryos) 　International：560USD
(Cryo Recovery) 　International：760USD
Last Update Date 2022/12/27
Analysis Data
  • Description
  • Genes &
    alleles
  • Phenotype
  • Health &
    husbandry
  • References
  • Specific Term
    and Conditions
  • Construct map
Species ： laboratory mouse
Strain Type ： COI (coisogenic strain),MSR (mutant strain)
Mutant Type ： TG (Transgenic),TM (Target Mutation)
Other Names ：
Background Strain ： 129
Strain Description ： 1. The offspring from 129-Cacna1htm2IBMS/CCC and mice carrying Myh7- YFP.
2. Deletion of exon 6 in Cacna1h gene, corresponding to amino acid 216 to 267
3. YFP-expressing mice.
4. Both homozygous male and female are smaller than their littermate controls.
5. Diffuse regions of cardiac fibrosis were observed in ventricular walls from 10-week old homozygotes, and the size of fibrosis is accompanied with increased age.
Homozygotes had impaired relaxation response and abnormal cardiac vasculature. 
Depositor ：
Chen, Chien-Chang / 陳建璋
Email ：
Allele Symbol ： cacna1htm2IBMS/CCC
Allele Name ： calcium channel, voltage-dependent, T type, alpha 1H subunit, target mutation 2, Chen, Chien-Chang,
Allele Description ：
Allele Symbol ： Tg(Myh7-YFP)IBMS/CCC
Allele Name ： Transgenic insertion, Chen, Chien-Chang
Strain of Origin ： 129
Gene Symbol ： Cacna1h
Gene Name ： calcium channel, voltage-dependent, T type, alpha 1H subunit
Chromosome ： 17
Gene Symbol ： Myh7
Gene Name ： myosin, heavy polypeptide 7, cardiac muscle, beta
Chromosome ： UN
Genotyping Method ： Download            
Genotyping NLAC ：            
Research Application ：
Cardiovascular Neurobiology Research
Construction Technologies ：
fluorescent proteins
Animal Health Reports ：
Colony Maintenance
Breeding & Husbandry 		：
Colony Maintenance
Mating System 		： homo x homo
References ： PubMed ID: 14631046

Specific Terms of Use ：
有特別規定
本生物材料僅限使用於學術研究。寄存者對於分讓申請人使用本材料 所獲得之研究成果，不主張任何專利、智慧財產權及其他財產權
DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of BIOLOGICAL RESOURCE for academic research purpose.
分讓申請人公開發表使用本材料所獲得之論文或其他研究成果時，應引用下述已發表之論文： Science. 2003 Nov 21;302(5649):1416-8
Should the use of this material result in one or more scientific
publication(s) the recipient agrees to cite the paper(s)： Science. 2003 Nov 21;302(5649):1416-8
分讓申請人向國研院動物中心國家實驗鼠種原庫(NLAC-RMRC)申請本材料時，應附上寄存人簽名之授權分讓同意書作為附件；NLAC- RMRC 在取得寄存人書面同意後，始進行此材料之分讓。
The recipient should obtain a written consent from the depositor of the BIOLOGICAL RESOURCE, prior to NLAC-RMRC accepting the material distribution request.
Depositor Email:
Construct Map ：
 
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